Context-processing deficits in schizophrenia: diagnostic specificity, 4-week course, and relationships to clinical symptoms.

Context Processing Deficits in Schizophrenia 1 Running Head: CONTEXT PROCESSING DEFICITS IN SCHIZOPHRENIA Context Processing Deficits in Schizophrenia: Diagnostic Specificity, Longitudinal Course, and Relationships to Clinical Symptoms

Specificity of Prefrontal Dysfunction and Context Processing Deficits to Schizophrenia in a Never Medicated First-Episode Psychotic Sample

Objective: Context processing is a cognitive construct associated with activity in middle frontal gyrus. Schizophrenia-related deficits in context processing tasks have been associated with prefrontal cortical dysfunction. This study evaluated whether context processing-related prefrontal cortical dysfunctions occurred in first-episode, never medicated schizophrenia patients, whether this also ...

Treatment-Responsiveness of Negative Symptoms in Schizophrenia: A double-blind placebo-control clinical trial

Background: The negative symptoms of schizophrenia remain a major clinical challenge. Nortriptyline is a serotonin and noradrenalin reuptake inhibitor and belongs to secondary amine tricycles. The aim of this study is to evaluate the effect of nortriptyline on the negative symptoms of schizophrenia. Methods: This study is a six-week randomized placebo-control trial of nortriptyline or placebo a...

Persistence, diagnostic specificity and genetic liability for context-processing deficits in schizophrenia.

Context-processing deficits have been shown in schizophrenia during first-episode, medication-naïve status, that persist after short-term antipsychotic treatment and also in first-degree relatives of individuals with schizophrenia. To confirm longer term persistence of deficits, we examined schizophrenia patients (n=63) during first-episode, medication-naïve status through to one-year follow-up...

Relationships Between Emotional Processing Deficits With Post-Traumatic Stress Symptoms, And Adherence To Treatment In Patient With Breast Cancer: The Mediating Role Of Cancer Stigma

Introduction: Negative emotions can have destructive effects on the treatment and recovery process of breast cancer patients. The present study aims to investigate relationships between emotional processing deficits with post-traumatic stress symptoms, and adherence to treatment in patient with breast cancer with the mediating role of cancer stigma. Methods: in terms of the purpose, the presen...